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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e566cf7345c8d1f92b659c4eb953b00c6e4089f721fd0366ee696312c666d1' 
  AND token = 'E9w+qq4BEOwLeZ2zsbAVXIoKMwuBuQbw6aYSlxdcyKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}