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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6bda5df64799be9dc7a08317a18d7ad3e45a7db4de9307802cff559a38d8d2' 
  AND token = 'r9YKFjf+29l+axYCSpL4gnz+TVltM5fVM0LShGpAjok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}