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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c334fd506bd9cb89abfc8bb0321bffc87fc172eeae6669a4b4ee24cd8b6de9d' 
  AND token = 'X9EnAxXhU1wcybyBPBZbr7dpLfvoASYmwgVtsfe+kIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}