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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec8ee6f8806aac11762a4ccc574efea1514c6722413810fc3cd2bab68c74cc2' 
  AND token = 'Iaf96Ew0NbTgHFM+UuqWto1TLrmiUNdCA3WeOTsHV5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}