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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7864f0cdc311088bd83682b7391115dabb9275b21d1c6ce6c096ed0bbf37e3' 
  AND token = 'ng/fkDpbWNmuMD97BzF/ve5v+PmgmqGIL1/Pa00LLuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}