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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb74b1a11a2293cf5e91e8a6e290a1124c8bc3dd828bb52a9588c783c31cd7a' 
  AND token = 'G5pYwEFK8UW+YVAXCUuRVsdYCW8chj4MY4MwrnLzBsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}