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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e639e909bc6207982cca1dc8224130017736f5008dc7a8614577de23a0c9736d' 
  AND token = 'TmlkOR45XHhK1lfxgdYH/jTdU7KphOJm0D9EHXQW/kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}