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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463e2ce85892171e56654ab935cd498235229ba9d7b3f298fd132971b88dfb09' 
  AND token = 'XAY3b/w2MnezB2pODFl6Ed/FSnKq4KdQ1KtF5emGWRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}