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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8e2732a25d974df618f59b94deac73272840e2170f759588c1ef15129eeb02' 
  AND token = 'U1zg/V3tMbhGLuQIC+hcRA7/wwGAbuezQU7k1ayXDsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}