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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc165aae64505137aab0645dec8db78262d3a6e34e3c7b355f95dffecec6b6e' 
  AND token = 'uC54KDLyEsQ5d402V2eBh+ZKKO6j9hxMxVm8+iHkaDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}