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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52249c55ecae413f69d27cdb83c1fff16ef85cf0e44a00193ca2d015b4a4dc26' 
  AND token = 'z6ohtk0hVlzds3yffYYFMjapCLRMIHzp+q+3vcSRdys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}