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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36b140f03b2bfa9809d5a1139afb851cc1d4c8a5af2e917a6b27173321cde6d9' 
  AND token = 'RL/L1zxZZowqznrVHQ9gl1FNNTupJb3pe1cNwhB62F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}