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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32607ece81522f26a7bb75616ee26674f4eafc8cd6b436d3238f1d33c0812b57' 
  AND token = 'BRPM41JEXQb/And6896hRr+o0b5GaIk/pumEh8gOCho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}