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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f5fde6972313e1a1df5a34c5bfd6b97c6e76cb6fc2e0c49165285d619d185f' 
  AND token = 'CFSAVsctYltz8ZK6xqhX4kHmfb9LV0IRDJF58PLK0M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}