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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861f72aef04833a61a9ee6f1e0cccc37e39cd145c9fe022e6f91ec133fac659c' 
  AND token = 'A1LuDWO1e0PNRrZEfKitgwtnqiRjnrv2ekJnApwEGsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}