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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728e23bdc60c972b0aa2000dfb627a2458e9657b9fb528ae8a5675bb6fd2335e' 
  AND token = 'C1uJjrVorqNR/bDEjgbV9kuy6mhYXs/Y4MjeRDHBZRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}