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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4acb2a592d41342aa5008fcfed5017c81b6cfc452c6fd21e295d0344d6c6466' 
  AND token = '0TkL2kYAv/7Aa/rwdXKR3IS+EBVSqU4seSdePlojDDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}