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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3e1dc039377e55227cf9e5723adf76fa7294f401917384e77db90b1bb9936c' 
  AND token = 'wftmqt5JETHBa62mICE8RTTchhFgESaFIau/ItkwIEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}