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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5e3ff996e0441de8e0fdf60a7d8cd6d000c9138c65401a5c393840f7fa3de6' 
  AND token = 'pG4WVG71Gqwy5Lif3+OlYskz6aUgV2Jjohmpi2IexcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}