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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a228552c747b05e199e4253c6e6021daac4b1910813cf7ce6e5468458a4cfdcd' 
  AND token = 'VI3pccKZjw5sraEyYYROQm99wQZE4VWaqetf/g4hOfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}