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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe705843df79b1645719add60b7fc2bc979322f2dbbb9199db6b514dada90746' 
  AND token = 'Z+Wfug0v4twz/7uuCOGGJ52X4b+4JUxZ107uRPHBr+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}