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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e541e83347393af668c517c3c7163c86a0045670cee7249fb0b9bc1b076721' 
  AND token = 'NG1ZJeFPk036W65WoUF493STz5G7CUmD2p6SO7fAFPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}