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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de915ac7bc4ee26388b8f10512b326c0f214905962a4b809f015f92eef8c72f2' 
  AND token = '1JLA1Bcn+pEkNXev2Tjj8RXgXu82AABEN191calw64I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}