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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f23ad113090cb19518e8db6301b67b56135ce1e2ffe06006841518d0620936' 
  AND token = 'QnpEZD7odO4GvCmqmNmIO0TVviPKiVHUFnzZ9O8SHb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}