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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85465a7d1aa87023ef24bcc3b58a9860862d6eb8e6771418609f5bb64b42ca02' 
  AND token = 'pRlk1xTjfgWj6hYOIVB/DN2gIIBsoKM1LDOjYDlAkIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}