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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75cac13a47c3077cd222c6af6d6d44451881670c161f916e441cf44cae678f3b' 
  AND token = 'RHQR0Z0E22apz5YwyHPz8M5U9iPI8sSUI58/x4SdohM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}