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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d362d5a6c788ca007e85a941bff85c41e37a457509d56db892923ca1f10ff78' 
  AND token = '292gyZ2gmE79xe8RV9AOJ5/LM8uubb0xvfbJkQ3KDaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}