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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e3707aa27577b4f857aa666df3aebf239819b452c65c9e60b3052445b50248' 
  AND token = 'Atk9cAo/fY7YAL/LfbMRg4hsPt9gW+7dsBX/wI4a1lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}