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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5f1f363a1608bb89696f34a72d990852e2228961f612b4628a25800c9b999f' 
  AND token = 'PKFf1QRbG0OUiH+FGveCq9S1fW07j87qVo2GH9Twtn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}