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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9db2ec1942b0623eb2dd9ad84d170d9a57770faeaccf22cf85bb02cb33130f72' 
  AND token = 'mAeOAgx3/lZ2ZLAjxG+nhRb5u+zEcrxWCgjYzU28x5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}