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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaba0d2d9e44114310875bdb2780e42a3e93187c58b8cdbd20c7acf53dad89d0' 
  AND token = 'wHF+5Jl/f+0rXdZIv3r3yUYLXoGktrRZvnH9gdFucdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}