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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3c5a776fa6317f79dbe3178f9f7f0efcc87b1b5aef8c61e259d4835b38c8e7' 
  AND token = 'ssOhldpYgS+ZRPiZEZuQcTWLFb9KDbDmPZd7i2KJKRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}