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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066d06e863a845162e51fa5cb3a44f927da4bf5d90d3729f4e7f2eeb6e5bf15c' 
  AND token = 'kHlKxVa0egEcinigMBTvPZugjat3y+qYwB6KIdqeiTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}