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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e994313736586fb677b32962761e9a678441aed9fd9726ed95db34246c699f' 
  AND token = 'ofN6Z6vdy9kCl5nQzJBEwJlJNTqOWWE3X37+kwZ7JkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}