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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a14f828e88f81042ec01a5acc34a3e082108e1aebd7a1651a397703c70e5e4f' 
  AND token = 'siFjUmtQY8U4I3V0TS5bKFt+OsRJWXWWYpPMHaZH6MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}