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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7dda65c5db7ce51bcae4a8578bd7b9b99bb8a47023732d79e05687517089aa2' 
  AND token = 'sJ60Bz3//kFoaznWsgsRld71fLV4So5UlQCSc8P5DPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}