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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fcac086a7cac56231660b0b9af33e6f4557b7e861134b2c22a71962165b163e' 
  AND token = 'HFHCzegs5hvxYXICEZmWsYzNDd70x1+kGAK8g60R1Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}