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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7825c10012d2027ebf844ac4c3499430c7541b9994329a97905491e970d99b' 
  AND token = 'Zb/oxMzl9raMEe40c9QruUv3hAintcWOW1QLxQM9jyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}