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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '794fdbb5e7b621685b3cd20d4337a6b1b0dd23bdd16fec637b11b5dee21434de' 
  AND token = 'Xwp8AG20JzCVTixkMWS2fY620yXSy8oXMNH729sccqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}