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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a1c0b628368166436d72b12d48b9b7c50608de22f22ee65207b329385e3373' 
  AND token = 'd82qXlClvnCm4ZxP9ZOT9mM7oSSqErnb3PYZaDg+7Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}