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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63f0234043eaf4cbe46954f831364ad24dae78d7a05bd4c4035da4a8d2f13363' 
  AND token = 'SzsyggSRAzcCCEbIWPBQd+wB1Od4oef2vU69v0LXoGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}