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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a80fb13bfa32477dee7be1909d597e23d42a8456f8e072c0c334bc7b5475a45' 
  AND token = 'eGOoMI88yoD10Hbt5AohvKih3OAZ2qRt1xiNii1Chu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}