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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a10aab13ad4232bc2d9eb4647a88eadb4bd85a47c66f56fa44f124da57fc46' 
  AND token = 'GIcCMZPy8+uHrPPVsZMk2JXwFrtEYc7ofrbNV1qYOts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}