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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665f9d18c13bcd67e23f2b62878de6474007d90b7ce9d500ac9443f3978dc64d' 
  AND token = 'uVsn2Kzsf05+rkJaEKcLjsHBvvucdWp1TogPZyn1A2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}