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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247dffa09505eb8e37e0e93d6001ac9ba7a7da59dec54f6e2b509dcbab4be801' 
  AND token = 'bgn4p3TUiQKf0Lzv52a4CrdGDPYQHWMPvDULDMy6v2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}