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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae09a6b0183f89a0e46ebadb13e04c80ea4e31906cb494914d15b2b1472f426' 
  AND token = 'ikSfmh52NlSvw4aTs3QKTae7h+WD84FXat3h7aEEWMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}