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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133955c1d61c4084311850113e272b396f2142f9e8733d01bc6883998a30a75b' 
  AND token = 'nR3pFoFupIvZNUK+ZzSDgGQfUzkn2AS74qygr+cZ8mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}