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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a7167bbef89a7b16b00a5e2296d13809fbac5ae9ff4e729f13d592a373c7ec' 
  AND token = 'OaS9t4OUB2ydmIDuMWbAwTDJGyk2iitmoWe/xD1OXU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}