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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c31ccc43a7ecb5cbb08988a3e083bb5283f2722abcc3d36afd7a4bc8ed0f1b8' 
  AND token = 'EBdBUFrtKS1P3cqXUBWU5VM4yGOWbpYAc92E3Vc0qtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}