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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf453524563f9092c34cf74f3afbf02e13179f4789908460cae913b2203658a' 
  AND token = 'WtIDxNSDDUdG8FQ4YtEwIKbC2UB81D6sxlKWMDvt/Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}